The documentary looks at the atrocities committed by the Japanese Unit 731 during the Second World War. During this time, Japan invaded other territories which included China and there was a need to develop biological weapons for it to grow as a superpower like the Soviet Union. The article, therefore, looks at the events that led to the development of Unit 731 and argues that a Japanese lieutenant by the name of Shiro Ishii wanted to establish himself as the father of biological weapons. This led to his establishment of a medical laboratory in Manchuria.

The documentary then goes ahead to explain how the unit brought together some of the best Japanese medical professionals and researchers. These individuals mainly investigated the development of biological weapons and used human beings of the Chinese and Russian descent as their test subjects. They would use their weapons to taste the effects of the weapons that they produced. They would also kill their subjects in different ways which included vivisection to see how much they suffered and the much they could endure before they died. This unit had support from both the Japanese governments and institutions of higher learning that provided resources in the form of research staff to help in the research.

Finally, it goes ahead to point out how this unit used the captured enemy soldiers as guinea pigs by infecting them with cholera, anthrax, and other diseases so that they could spread it with their colleagues. It shows how the unit covered its tracks before it surrendered its invasion in China by destroying the laboratory and killing all the remaining prisoners.